Endocrine Abstracts

Introduction: Congenital hypothyroidism (CH) is defined as thyroid hormone deficiency which is present at birth. Thyroid hormones are crucial for early neurodevelopment. Untreated severe CH results in major neurological deficits. Therefore, if treatment is initiated early, these deficiencies can be prevented. Newborn screening for CH was first initiated in Sri Lanka in September 2010.Methods: A retrospective cohort study...

The Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome is characterized by congenital absence or underdevelopment of the uterus and upper two thirds of the vagina in females with karyotype XX, alongside normal external genitalia. The prevalence is 1 in 4000 to 5000. It can be divided into two major categories. Type 1 occurs in isolation whilst type 2 involves other organ systems, particularly the renal, vertebral, auditory and cardiac systems. Whilst sporadic i...